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Structural comparison of DERA monomers. Structures of the DERAPae (A) and DERATma (B) monomers (green) superimposed on the DERAEco monomer (yellow) are shown. The N-terminal α helix of DERATma is indicated by an arrow. The DRP binding site of the hyperthermophilic DERAs has been predicted based on their superposition with DERAEco in complex with DRP. The DRP molecule is represented by a stick model (red).
