FIG. 2.

Monoinfection with wild-type E. faecalis OG1RF and its isogenic mutants. Data are from 15 mice infected with 10⁴ CFU; results are expressed as log₁₀ CFU per gram from kidney homogenates 48 h after transurethral challenge. The log₁₀ CFU from both kidneys were combined and averaged. A value of 1 was assigned to those kidneys with 0 CFU. Triangles represent wild-type E. faecalis OG1RF, circles represent OG1RF ΔsrtA, diamonds represent OG1RF Δbps, and squares represent OG1RF ΔsrtA Δbps. Horizontal bars represent the geometric mean. The mean difference in CFU counts of sortase mutants versus OG1RF is given as the log₁₀ ± the standard deviation (SD). Differences in the log₁₀ CFU of OG1RF versus the ΔsrtA, Δbps, and ΔsrtA Δbps mutants recovered from organs were evaluated by the unpaired t test.