TABLE 3.
Peptide | Amino acid sequence | Relative responsea |
---|---|---|
1 | IGYSMDGPRVEFEVSYb | 1.00 |
2 | GYSMDGPRVEFEVSY | 1.33 |
3 | YSMDGPRVEFEVSY | 1.38 |
4 | SMDGPRVEFEVSY | 1.36 |
5 | MDGPRVEFEVSY | 0.35 |
6 | DGPRVEFEVSY | 0.04 |
7 | GPRVEFEVSY | 0.17 |
8 | IGYSMDGPRVEFEVS | 1.47 |
9 | IGYSMDGPRVEFEV | 1.45 |
10 | IGYSMDGPRVEFE | 1.12 |
11 | IGYSMDGPRVEF | 0.003 |
12 | IGYSMDGPRVE | 0.001 |
13 | IGYSMDGPRV | 0.001 |
IL-2 production in response to the truncated peptides is indicated relative to the response achieved using the full-length peptide (1).
The underlined sequence indicates the minimal T-cell epitope required for T-cell activation.