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. 2007 Sep 4;75(11):5240–5247. doi: 10.1128/IAI.00884-07

FIG. 1.

FIG. 1.

Time to death of A/J mice after immunization with rBclA (alone) followed 4 weeks later by subcutaneous challenge with 10 LD50s of B. anthracis Sterne strain 34F2 spores (∼104 spores). The MTD for the vaccinated group was 4.8 days; the MTD for the group given PBS (mixed 1:1 with Titermax) was 4.1 days. This difference in the MTD was statistically significant (P = 0.0045) by the Kaplan-Meier test. The average anti-rBclA ELISA OD450 response for a 1:100 serum dilution of the rBclA-immunized mouse group was 1.6 (data not shown).