FIG. 3.

Antibodies induced by C/C and F+C/M+C immunization bind specifically to the linear B-cell epitope DP4 and P. berghei sporozoites. BALB/c mice were immunized with the C/C or F+C/M+C regimen. The interval between prime and boost was 2 weeks. Two weeks after boosting (day 28), blood was collected from the tail vein and sera assayed for anti-DP4 specific IgG responses by ELISA and IFA. Results are representative of two experiments and are expressed as log-transformed end point titers ± 95% confidence interval (n = 4). **, P ≤ 0.01.