TABLE 1.
Immunization regimens
| Immunization | Immunizationa
|
|
|---|---|---|
| Priming (day 0) | Boosting (day 14 or 21) | |
| C/C | CV-1866 i.d. or i.p. | CV-1866 i.d. or i.p. |
| F/M | FP.PbCSP i.d. | MVA.PbCSP i.d |
| F,C/M,C | FP.PbCSP i.d., CV-1866 i.p. | MVA.PbCSP i.d., CV-1866 i.p. |
| F+C/M+C | FP.PbCSP + CV-1866 mixed i.d. | MVA.PbCSP + CV-1866 mixed i.d. |
| Fnr+C/Mnr+C | FP.LacZ + CV-1866 mixed i.d. | MVA.LacZ + CV-1866 mixed i.d. |
a
Doses and routes for vaccines: 5 μg or 10 μg of CV-1866 i.d. or i.p., respectively; 1 × 106 PFU of recombinant (F and M) and nonrecombinant virus (Fnr and Mnr), both i.d.