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. 2007 Sep 24;75(12):5698–5710. doi: 10.1128/IAI.00175-07

FIG. 1.

FIG. 1.

Presence and organization of the S. pyogenes ES and ERES gene blocks in GAS strains belonging to various serotypes. The organization of both regions is shown for different S. pyogenes strains whose genomes have been sequenced. The data were extracted from the genome sequences at NCBI. The SPy numbering is the numbering for the serotype M1 genome sequence (15). eno encodes GAS enolase; sagA encodes GAS streptolysin S; ralp3 encodes GAS RofA-like protein 3; epf encodes a novel GAS plasminogen-binding protein; and ncRNA is a putative untranslated small RNA species. The accession number and strain of each serotype used for the comparative analysis are as follows: serotype M1, accession number NC_002737 and strain SF370; serotype M2, NC_008022 and MGAS10270; serotype M3, NC_004606 and SSI-1; serotype M4, NC_008024 and MGAS10750; serotype M5, NC_009332 and Manfredo; serotype M6, NC_006086 and MGAS10394; serotype M12, NC_008023 and MGAS2096; serotype M18, NC_003485 and MGAS8232; serotype M28, NC_007296 and MGAS6180; and serotype M49, AAFV00000000 and 591.