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. 2007 Oct 3;14(12):1644–1645. doi: 10.1128/CVI.00100-07

TABLE 1.

Comparison CD14 polymorphisms and “risk” genotypes (CD14-159CC, FcγRIIA-R/R131) between Hong Kong patients with SARS and control group of Hong Kong blood donors

Factor No. (%) of:
SARS patients (n = 152)a
Blood donors (n = 198)
Mild Severe (ICU)c
Presence of CD14-159 polymorphismb
    CC 19 (15) 8 (31) 39 (20)
    CT 67 (53) 14 (54) 95 (48)
    TT 40 (32) 4 (15) 64 (32)
Presence of risk genotypes 30 (24) 12 (46) 53 (27)
Absence of risk genotypes 96 (76) 14 (54) 145 (73)
a

Mild SARS refers to patients who recovered without the need for intensive care or ventilation.

b

The difference in linear tread distribution of CD14-159 genotypes (CC, CT, and TT) between the ICU and mild SARS groups was significant (two-by-three contingency table; P = 0.027).

c

In comparison with the mild SARS group and controls, the incidence of patients carrying risk genotypes in the severe SARS (ICU) group is significantly higher (two-by-two contingency table; for mild SARS, two-sided P = 0.029; odds ratio, 2.74 [1.15 to 6.57]; for controls, P = 0.04; odds ratio, 2.41 [1.05 to 5.54] for controls.