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Tissue fungal burden following Histoplasma capsulatum infection. Groups of mice were infected intranasally with 2 × 106 yeast cells of H. capsulatum strain G217B or the hygromycin-resistant G217B derivative UC1. CFU in lungs (A) and spleens (B) were counted on day 7 (n = 13) or day 9 (n = 10) after infection. Data are means ± standard errors. *, P < 0 0.05; **, P < 0.0001.
