TABLE 3.

OPS gene cluster of Y. enterocolitica O:9: genes, gene products, and similarities

Gene	Protein	Size (no. of amino acids)	Similarity	Putative function(s)
orf1	Orf1	>117	80-98% identity	N terminus: similar to TerC-family proteins, possibly involved in tellurite resistance
manC	ManC	472	>70% identity to several ManC proteins	Mannose-1-phosphate guanylytransferase; involved in biosynthesis of GDP-mannose and GDP-N-formylperosamine
manB	ManB	480	>70% identity to several ManB proteins	Phosphomannomutase; involved in biosynthesis of GDP-mannose and GDP-N-formylperosamine
galU	GalU	296	80-98% identity to several GalU proteins	UTP-glucose-1-phosphate uridylyltransferase
galF	GalF	297	80-98% identity to several GalU proteins	UTP-glucose-1-phosphate uridylyltransferase; 66% identical to GalU of same strain.
gmd	Gmd	373	>80% identity to several Gmd proteins	GDP-mannose-4,6-dehydratase; involved in biosynthesis of GDP-N-formylperosamine
per	Per	361	55-67% identity to several Per proteins	GDP-d-perosamine synthase; involved in biosynthesis of GDP-N-formylperosamine
wzm	Wzm	260	55-71% identity to several Wzm proteins	Putative ABC transporter system integral membrane protein; translocation of OPS
wzt	Wzt	251	45-78% identity to several Wzt proteins	Putative ATP binding protein involved in OPS export
wbcT	WbcT	581	37% identity to glycosyltransferase of Aeromonas hydrophila	Involved in biosynthesis of O:9 OPS, N-terminal half 55% identical to WbkB, a putative glycosyltransferase of Brucella
wbcU	WbcU	527	30-40% identity to mannosyltransferases	Putative N-formylperosaminyltransferase; amino acids 1 to 75 and 192 to 527 similar to Brucella mannosyltransferase
wbcV	WbcV	260	40-50% identity to several N-formyltransferase proteins	Putative N-formyltransferase; involved in biosynthesis of GDP-N-formylperosamine
wbcW	WbcW	370	45-55% identity to glycosyltransferases	Putative N-formylperosaminyltransferase
gnd	Gnd	390	85-98% identity to several Gnd proteins	Gluconate-6-phosphate dehydrogenase