TABLE 4.
Competitive growth assays of the pcgC mutant and complemented strains
| Strain | Description | rCI ± SDa | Infection route |
|---|---|---|---|
| AL571 | PCho−; pcgC mutant | 0.1 ± 0.1 | i.m. |
| AL571 | PCho−; pcgC mutant | 0.003 ± 0.008 | i.t. |
| AL829 | PCho+; pcgC mutant complemented with pcgC | 0.5 ± 0.1 | i.m. |
| AL831 | PCho−; pcgC mutant harboring pAL99 | 0.01 ± 0.01 | i.m. |
a
rCI values were calculated for individual animals by dividing the in vivo competitive index (CI) by the in vitro CI, and the values shown are the average rCI values for three replicate animals ± 1 standard deviation (SD). Each CI value was determined by dividing the output mutant/wild-type ratio by the input mutant/wild-type ratio.