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Comparison of modern H1N1 virus to the 1918 “Spanish Flu” strain. (A) Layout of MChip with 15 sequences (open circles) spotted in triplicate next to a column of control spots (filled circles). (B) Fluorescence image from a New Caledonia-like A/H1N1-infected clinical sample obtained after 2000 (from the Colorado Department of Public Health and Environment). Brighter spots indicate higher fluorescence intensity. (C) Fluorescence image from A/Brevig Mission/1/1918.
