TABLE 1.
Analysis of four diagnostic tests used in the evaluation of 62 lesions suspected to be CLa
| Assay | No. of positive samples | No. of negative samples | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|
| LSTb | 43 | 17 | 84.3 | 100 | 100 | 52.9 |
| Smear | 45 | 17 | 84.9 | 100 | 100 | 52.9 |
| kDNA PCR | 57 | 5 | 94.3 | 22.2 | 87.7 | 40 |
| All cultures | 39 | 23 | 73.6 | 100 | 100 | 39.1 |
| MCM | 38 | 24 | 71.7 | 100 | 100 | 37.5 |
| TCM NNN | 29 | 33 | 54.7 | 100 | 100 | 27.3 |
| TCM RPMI | 19 | 43 | 35.8 | 100 | 100 | 20.9 |
a
LST, leishmanin skin test; MCM, microculture method; TCM, traditional culture method; NPV, negative predictive value; PPV, positive predictive value.
b
Two individuals did not undergo leishmanin skin testing.