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. 2007 Jun 27;45(11):3713–3720. doi: 10.1128/JCM.02012-06

TABLE 3.

Results of in vitro antifungal susceptibility testinga

Organism or type MIC (mg/liter)
Amphotericin B
Itraconazole
Voriconazole
Posaconazole
MIC50 MIC90 MIC50 MIC90 MIC50 MIC90 MIC50 MIC90
E. phaeomuriformis 0.5 1 ≤0.015 0.03 0.03 0.06 ≤0.015 ≤0.015
E. xenobiotica 0.25 0.5 0.03 0.125 0.125 0.5 ≤0.015 0.03
E. bergeri 0.25 0.25 0.125 0.25 1.0 1.0 0.03 0.03
E. lecanii-corni 0.25 0.5 0.06 0.125 0.06 0.5 ≤0.015 0.03
E. spinifera 0.5 0.5 0.03 0.06 0.125 0.5 ≤0.015 0.03
E. jeanselmei 0.5 1 0.03 0.06 0.125 0.25 ≤0.015 0.03
E. mesophila 0.25 0.5 0.125 0.25 0.5 0.25 0.06 0.06
E. dermatitidis 0.5 1.0 0.125 0.25 0.125 0.25 0.03 0.06
E. oligosperma 0.25 0.5 0.06 0.125 0.25 1.0 0.03 0.03
Susceptibleb ≤1.0 ≤0.5 ≤2.0 ?
Resistantc >2.0 ≥1.0 >2.0 ?
a

No defined breakpoints are available for the genus Exophiala, and the clinical correlates are primarily anecdotal. AMB, amphotericin B, ITRA.

b

Suggested MIC for clinical efficacy based upon in vitro data.

c

Suggested MIC for less than favorable clinical outcome based upon in vitro data.