TABLE 1.
Codon | Isolate typea | Mutation detected
|
Clinical relevance of the mutation | |
---|---|---|---|---|
Previous strip (INNO-LiPA HBV DR) | Updated strip (INNO-LiPA HBV DR v2) | |||
80 | WT | L80 | Possibly relevant for lamivudine (compensatory mutation) | |
MUT | V80 | |||
MUT | I80 | |||
173 | WT | V173 | Possibly relevant for lamivudine (compensatory mutation) | |
WT | G173 | |||
MUT | L173 | |||
180 | WT | L180 | L180 | Relevant for lamivudine |
MUT | M180 | M180 | ||
181 | WT | A181 | Possibly relevant for lamivudine and adefovir | |
MUT | T181 | |||
MUT | V181 | |||
204 | WT | M204 | M204 | Relevant for lamivudine |
MUT | V204 | V204 | ||
MUT | I204 | I204 | ||
MUT | S204 | |||
207 | WT | V207 | No longer relevant (famciclovir) | |
WT | L207 | |||
WT | M207 | |||
MUT | I207 | |||
236 | WT | N236 | Relevant for adefovir | |
MUT | T236 |
WT, wild type; MUT, mutant.