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Correlation between the degree of cytoplasmic and nuclear HBcAg staining and the logarithmic reduction in level of HBcrAg at week 48 of therapy
| Location | % of cells that stained pos at wk 48 for HBcAg | No. of patients | Median reduction in HBcrAg (log10 kU/ml) | P value |
|---|---|---|---|---|
| Cytoplasm | 0 | 26 | 1.87 | 0.017 |
| ≤5 | 8 | 1.36 | ||
| 6-25 | 3 | 0.5 | ||
| 26-50 | 1 | 0.3 | ||
| Nucleus | 0 | 27 | 1.75 | |
| ≤5 | 7 | 1.34 | 0.007 | |
| 6-25 | 4 | 0.4 |
