FIG. 11.

Inversions in the lineage of Streptomyces and Thermobifida fusca chromosomes. Dotted lines indicate the nonconserved ends of linear Streptomyces chromosomes (the T. fusca chromosome is circular). The origin of replication is indicated by a shaded oval. Connected arrows indicate inversion events deduced from overall synteny plots between chromosomes (65, 75, 194, 442). The diagram should be taken as an approximation of both the positions and frequencies of such events. There is only one clear example of a substantial inversion event that does not span the origin of replication (boldface arrows).