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Adhesion of a ΔhrpA deletion mutant and a ΔhrpB deletion mutant of strain 2517 ΔlgtA to HEp2 (A) and FaDu epithelial cells (B) 5 h p.i. Compared to the wild-type (wt) parental strain, the proportion of cell-associated bacteria was significantly lower in the ΔhrpA mutant and in the ΔhrpB mutant. Means plus standard deviations (error bars) for 10 independent experiments are indicated. Two-tailed Student's t test was used to calculate statistical significance (P values).
