Figure 1.

Isolation of TAF_II250 by yeast two-hybrid screening by using a second exon Tat fragment. (A) Map of the entire human TAF_II250 protein indicating the regions containing the CCG1 mutation and the 5′ and 3′ kinase domains as well as the histone acetylase (HA) domain. The region homologous to the cloned mouse TAF_II250 segment that interacts with the second exon of Tat is noted. (B) Homology of the translated mouse TAF_II250 HincII fragment with the human and drosophila TAF_II250 protein sequences.