FIG. 6.

Proposed functional arrangement of HgdD (Alr2887). The structural composition of the HgdD/DevABC complex is shown, as discussed in the text. HgdD was modeled as shown in Fig. 2A, DevA was modeled using MJ0796, a bacterial ATP binding cassette (PDB:1L2T), as the template, and sections of DevB were modeled using MexA (PDB:1VF7) as the template. The pink boxes represent an extension of the two-helix coiled coil of DevB bridging the periplasm and attaching to HgdD (Alr2887). The ellipse with a question mark indicates that further elements stabilizing the complex might exist. OM, outer membrane; PM, cytoplasmic membrane.