TABLE 3.
Virus-neutralizing antibodies in vaccinated monkeysa
| Vaccine group | Animal | PRNT50
|
||
|---|---|---|---|---|
| Day 140 | Day 252 | Day 262 | ||
| DDD | 16676 | 1,569 | 983 | 6,181 |
| 16678 | 1,014 | <80 | 6,483 | |
| AV9K | 1,510 | 668 | 2,455 | |
| VVV | 16904 | 2,369 | 581 | 5,819 |
| 16796 | 1,321 | 582 | 3,605 | |
| 16642 | 1,933 | 1,475 | 4,163 | |
| AA4B | <80 | <40 | 4,584 | |
| DDV | 16620 | 2,178 | 1,028 | 5,151 |
| 16871 | 2,509 | 2,638 | 3,675 | |
| 16881 | 2,820 | 1,696 | 4,082 | |
| AA3W | 1,707 | 582 | 3,786 | |
a
Sera obtained on day 140, day 252 (day of virus challenge), and day 262 (10 days postchallenge) were used to determine virus neutralization titers by PRNT. PRNT50s were determined by probit analysis. “<x” denotes <50% neutralization at the lowest dilution (x) used in the assay. Data are representative of two independent determinations.