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Inverse linear correlation between HIV disease progression markers at baseline and the subsequent loss of Gag-specific breadth in T-cell recognition. Shown are the net change in the breadth of Gag-specific peptide pool responses over a 9-month interval (x axis) and the baseline viral load (A) or the baseline CD4 cell count (B) for each subject (n = 33). For one subject, the baseline viral load was not determined. GraphPad Prism software was used for the linear regression analysis.
