FIG. 3.
Notch signaling in the ocular lens. (A) In situ hybridization of Herp2 in a section of an E17.5 wild-type lens. Note the orientation of the sections: anterior up and posterior down, as shown in Fig. 1. (B) In situ hybridization of p57Kip2 in an adjacent section of panel A. (C) In situ hybridization of Herp2 in a section of an E17.5 Rbp-J mutant lens. (D) Immunofluorescent staining of Jag1 and p57Kip2 in sections of an E17.5 wild-type lens. The sections were counterstained for DNA with DAPI. Scale bars, 50 μm.