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Suppression of p57Kip2 promoter in mammalian cells. (A) Diagrams showing the CAT constructs. (B) Herp2 and Herp3 suppress CAT reporter expression driven by the p57Kip2 promoter. CAT expression in empty vector-transfected cells was set to 1.0. Error bars indicate standard deviations. (C) ChIP assay results demonstrating the interaction of Herp2 with the E-I region of p57Kip2 in NIH 3T3 cells.
