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. 2007 Sep 5;81(22):12135–12144. doi: 10.1128/JVI.01296-07

TABLE 1.

Engineered mutations in ExoN mutant viruses

Virus Engineered mutationsa Amino acid substitutionsb
rExoN1 A18426C, U18427A Asp89Ala
A18432C, A18433U Glu91Ala
rExoN3 A18975C, U18976G Asp272Ala
C18989G, G18990C Arg277Ala
a

Nucleotide positions refer to the MHV-A59 complete genome sequence (GenBank accession no. AY910861).

b

Amino acid positions refer to nsp14 sequence (ORF1a/b polyprotein residues 5985 to 6505).