TABLE 2.

Frequencies of resistance-conferring mutations in RT of virus from macaque M03250 before and during treatment as determined by SGS^a

Wk postinfection	Wk post-initiation of treatment		Frequency of mutation (%)b
			K65Rc	L100I	K103N		M184Ic	M184Vc
	EFV	ART			AAC	AAT
13	0	0	—	—		—	—	—
17	4	0	—	2	10	5	—	—
19	NAd	2	—	—	17	—	—	—
22	NA	5	3	—	19	5	—	—
23	NA	6	24	—	42	3	9	—
24	NA	7	—	—	43	—	42	—
25	NA	8	2	—	95	—	89	—
26	NA	9	—	—	98	—	93	5

^aApproximately 35 separate genomes were analyzed for each time point.

^b—, none detected.

^cDrug resistance-conferring mutation genetically linked to K103N (AAC) on all genomes.

^dNA, not applicable.