TABLE 2.
Tumor incidence and type in Pold1+/+, Pold1+/L604G, and Pold1+/L604K micea
| Strain | No. (%) of:
|
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total mice | Mice with tumors | Mice with no tumors | Mice with malignant tumors | Mice with multiple tumors | Neoplasms/mouse | Tumor types | Epithelial tumors | Bronchiolo-alveolar tumors | Hepatocellular tumors | Other tumors | Mesenchymal tumors | Lymphoreticular tumors | Other tumors | |
| Wild type | 47 (100) | 29 (62) | 18 (38) | 23 (79)b | 9 (19) | 1.8 | 10 | 20 (43) | 6 (13) | 11 (23) | 3 (6) | 17 (36) | 14 (30) | 3 (6) |
| L604G | 59 (100) | 46 (78) | 13 (22) | 39 (85)b | 15 (25) | 2.2 | 11 | 33 (56) | 11 (19) | 19 (32) | 3 (5) | 31 (53) | 26 (44) | 5 (8) |
| L604K | 64 (100) | 45 (70) | 19 (30) | 37 (82)b | 6 (9) | 1.9 | 13 | 23 (36) | 8 (13) | 10 (16) | 5 (8) | 28 (44) | 22 (34) | 6 (9) |
a
The number and percentage of affected mice are shown.
b
Percentage of mice with tumors.