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. 2007 Sep 26;81(23):12785–12792. doi: 10.1128/JVI.01732-07

FIG. 5.

FIG. 5.

Location of amino acid residues in the Ad35 fiber knob that are involved in binding to CD46. (A to E) Amino acids in the HI and FG loops, identified through library or model structure analysis, that are involved in HI-FG loop interaction or binding to CD46 domain SCR1. (F to H) Amino acids in the IJ and GH loops, identified through library or structural analysis, that are involved in IJ-GH loop interaction or binding to CD46 domain SCR2. Hydrogen bonds are indicated by dashed yellow lines, and salt bridges are indicated by dashed orange lines.