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Elk-1 and SRF activate the HTLV-1 LTR. 293 cells were transfected with reporter plasmids containing either the wild-type LTR (white bars) or an LTR containing mutations in all three vSRE elements (mvSRE) (black bars) along with 0.5 μg of pRSV-Elk-1-RSPA, 0.5 μg of pSG-SRF, or 0.5 μg of Elk-1 and pSG-SRF expression plasmid. These results are the averages for three independent experiments.
