TABLE 2.
Promoters bound by Rds2a
| Systematic name | Gene | Function | Binding enrichmentb
|
|
|---|---|---|---|---|
| Glucose | EtOH | |||
| YKR097W | PCK1 | Phosphoenolpyruvate carboxykinase | 32.8 | 20.5 |
| YGR244C | LSC2 | Beta subunit of succinyl-CoA ligase | 3.3 | 17.2 |
| YEL060C | PRB1 | Vacuolar protease B | 1.1 | 16.7 |
| YNL065W | AQR1 | Multidrug resistance transporter | 4.7 | 14.0 |
| YLR377C | FBP1 | Fructose-1,6-bisphosphatase | 1.0 | 12.2 |
| YBR105C | VID24 | Peripheral vesicle membrane protein | 4.1 | 11.4 |
| YKL029C | MAE1 | Malic enzyme | 5.1 | 10.0 |
| YKL109W | HAP4 | Transcriptional activator of respiratory genes | 1.2 | 8.6 |
| YLR044C | PDC1 | Pyruvate decarboxylase | 3.3 | 6.7 |
| YHL020C | OPI1 | Transcriptional repressor of phospholipid biosynthetic genes | 2.0 | 6.4 |
| YMR195W | ICY1 | Protein that interacts with the cytoskeleton and is involved in chromatin organization and nuclear transport | 1.5 | 4.3 |
| YOL109W | ZEO1 | Peripheral-membrane protein of the plasma membrane that interacts with Mid2 | 1.0 | 3.6 |
| YDR148C | KGD2 | Alpha-ketoglutarate dehydrogenase complex dihydrolipoyl transsuccinylase component | 0.9 | 3.3 |
| YLR056W | ERG3 | C-5 sterol desaturase | 1.4 | 3.1 |
| YLR055C | SPT8 | Probable member of histone acetyltransferase SAGA complex transcription factor | 1.4 | 3.1 |
| YLR174W | IDP2 | NADP-dependent isocitrate dehydrogenase | 1.0 | 3.0 |
| YGR044C | RME1 | Zinc finger protein negative regulator of meiosis | 0.8 | 3.0 |
| YLR153C | ACS2 | Acetyl-coenzyme A synthetase | 0.8 | 2.8 |
| YJR095W | SFC1 | Succinate-fumarate transport protein | 1.2 | 2.8 |
| YOL136C | PFK27 | 6-Phosphofructo-2-kinase | 0.9 | 2.7 |
| YDR178W | SDH4 | Succinate dehydrogenase membrane anchor subunit | 0.9 | 2.6 |
| YJL219W | HXT9 | Hexose permease | 1.3 | 2.5 |
| YKL203C | TOR2 | Putative protein/phosphatidylinositol kinase involved in signaling activation of translation initiation, distribution of the actin cytoskeleton, and meiosis | 0.8 | 2.5 |
| YNR001C | CIT1 | Citrate synthase | 1.0 | 2.5 |
| YMR135C | GID8 | Involved in proteasome-dependent catabolite inactivation of FBPase | 1.2 | 2.4 |
| YNL117W | MLS1 | Carbon-catabolite-sensitive malate synthase | 0.9 | 2.3 |
| YHR051W | COX6 | Cytochrome c oxidase subunit | 0.9 | 2.2 |
| YPR074C | TKL1 | Transketolase 1 | 0.9 | 2.1 |
| YAR035W | YAT1 | Carnitine acetyltransferase | 1.0 | 2.0 |
| YJR048W | CYC1 | Iso-1-cytochrome c | 1.4 | 2.0 |
| YJL089W | SIP4 | Transcriptional activator that binds to the CSRE of gluconeogenic genes | 0.8 | 1.7 |
a
P < 0.005 under at least one condition.
b
Enrichment values for ChIP-chip analysis performed with cells grown with glucose or ethanol (EtOH) as described in Materials and Methods.