TABLE 1.
Predicted NMD sensitivity and SECIS forms
| Selenoprotein | No. of exons | Position of intron relative to UGA codon
|
Subject to NMD | SECIS form(s) | |
|---|---|---|---|---|---|
| Distance from codon (bp)a | Direction | ||||
| Dio1 | 4 | 105 | Downstream | Yes | 1 |
| Dio2 | 2 | 174 | Upstream | No | 2 |
| Dio3 | 1 | No EJC | No | 2 | |
| Gpx1 | 2 | 105 | Downstream | Yes | 1 |
| Gpx2 | 2 | 105 | Downstream | Yes | 1 |
| Gpx3 | 5 | 141 | Downstream | Yes | 2 |
| Gpx4 | 7 | 10 | Downstream | Yes | 2 |
| Gpx6 | 5 | 141 | Downstream | Yes | 2 |
| SelH | 4 | 135 | Downstream | Yes | 2 |
| SelI | 10 | 66 | Upstream | No | 2 |
| SelK | 5 | 6 | Downstream | No | 2 |
| SelM | 7 | 138 | Downstream | Yes | 2 |
| SelN | 13 | 162 | Downstream | Yes | 1 |
| SelO | 10 | 330 | Upstream | No | 2 |
| SelP | 5 | 240 | Downstream | Yes | 1, 2 |
| SelR | 4 | 36 | Downstream | No | 2 |
| SelS | 7 | 6 | Downstream | No | 2 |
| SelT | 6 | 141 | Downstream | Yes | 2 |
| SelV | 6 | 72 | Downstream | Yes | 1 |
| SelW | 6 | 72 | Downstream | Yes | 2 |
| Sel15 | 5 | 78 | Downstream | Yes | 2 |
| Sps2 | 1 | No EJC | No | 2 | |
| Trxr1 | 15 | 63 | Upstream | No | 2 |
| Trxr2 | 18 | 65 | Downstream | Yes | 2 |
| Trxr3 | 16 | 69 | Upstream | No | 2 |
a
EJC, exon junction complex.