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ERGs recorded from 6-week-old Otx2 CKO and control mice. (A) Dark-adapted ERGs elicited with six different stimulus intensities. (B) Light-adapted ERGs elicited with four different stimulus intensities. Vertical dotted lines show the onset of the stimulus. The ERGs of an Otx2 CKO mouse showed a selective reduction of the b-wave amplitude which originates from bipolar cells in both rod and cone pathways.
