TABLE 1.
Clonal composition following infection of Otx2flox/flox retinas with retroviruses encoding cre recombinase
| Litter no. or parameter, virus | No. of clones containing at least one of the following/total (%):
|
No. of rod-only clones/total (%) | |||
|---|---|---|---|---|---|
| Rod | Bipolar | Amacrine | Müller | ||
| 1, LIA | 126/135 (93.3) | 34/135 (25.2) | 14/135 (10.4) | 7/135 (5.2) | 90/135 (66.7) |
| 2, LIA | 121/128 (94.5) | 30/128 (23.4) | 7/128 (5.5) | 11/128 (8.6) | 83/128 (64.8) |
| 3, LIA | 225/241 (93.4) | 53/241 (22.0) | 21/241 (8.7) | 11/241 (4.6) | 159/241 (66.0) |
| 4, LIA | 229/243 (94.2) | 46/243 (18.9) | 21/243 (8.6) | 9/243 (3.7) | 169/243 (69.5) |
| 5, LIA | 350/380 (92.1) | 78/380 (20.5) | 37/380 (9.7) | 19/380 (5.0) | 256/380 (67.4) |
| 6, LIA-Cre | 55/91 (60.4) | 3/91 (3.3) | 48/91 (52.7) | 9/91 (9.9) | 33/91 (36.3) |
| 7, LIA-Cre | 138/235 (58.7) | 4/235 (1.7) | 125/235 (53.2) | 18/235 (7.7) | 93/235 (39.6) |
| 8, LIA-Cre | 177/336 (52.7) | 9/336 (2.7) | 181/336 (53.9) | 17/336 (5.1) | 141/336 (42.0) |
| 9, LIA-Cre | 271/479 (56.6) | 2/479 (0.4) | 235/479 (49.1) | 17/479 (3.5) | 235/479 (49.1) |
| Mean ± SD (%) | |||||
| LIA | 93.5 ± 0.9 | 22.0 ± 2.5 | 8.6 ± 1.9 | 5.4 ± 1.9 | 66.9 ± 1.8 |
| LIA-Cre | 57.1 ± 3.3 | 2.0 ± 1.3 | 52.0 ± 1.9 | 6.6 ± 2.8 | 41.8 ± 5.4 |