Figure 1.
Schematic structure of rhodopsin. Each amino acid residue is shown as a green dot; amino acid residues that are mutated in patients with retinitis pigmentosa are shown as red dots. Seven transmembrane domains are boxed. Mutations are collected from the Human Gene Mutation Database (www.hgmd.org), the Retinal Information Network (www.sph.uth.tmc.edu/RetNet/sym-dis.htm), and the Retina International Mutation Database (www.retina-international.com/sci-news/rhomut.htm) and references [88] and [89].