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. 1999 Nov 29;147(5):995–1008. doi: 10.1083/jcb.147.5.995

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© 1999 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Neonatal cardiomyocytes of ankyrin-B (−/−) mice exhibit abnormal distribution of SR CaATPase (SERCA) and ryanodine receptors and normal localization of α-actinin and dihydropyridine receptors. A–C show immunofluorescent labeling of ankyrin-B (+/+) (left) and (−/−) (right) cardiomyocytes double-labeled with antibodies against α-actinin (A1) and SERCA 2 (A2) (A); antibodies against the ryanodine receptor type 1 and 2 (B) and antibody against the dihydropyridine receptor (voltage-sensitive calcium channel) (C). Bars, 10 μm.