TABLE 1.
Genotype and test parameter | No. of progeny | No. of cd44−/−; x+/− (%) | No. dead (%) | No. with lungs that sank (%) |
---|---|---|---|---|
Cross of cd44−/−; x+/+ and cd44+/−; x+/− | ||||
Survival | ||||
x = met | 152 | 36 (24) | 25 (70) | |
x = hgf | 208 | 56 (27) | 33 (60) | |
x = gab1 | 143 | 32 (22) | 22 (69) | |
Lung assay | ||||
x = met | 85 | 21 (25) | 16 (76) | |
x = hgf | 97 | 23 (23) | 12 (52) | |
x = gab1 | 84 | 21 (25) | 13 (62) | |
Backcross of cd44−/−; x+/− and cd44−/−; x+/+ | ||||
Survival, x = met | 55 | 13 (24) | 9 (69) | |
Lung assay, x = met | 63 | 19 (30) | 8 (42) |