Figure 4.
Involucrin-Dsg 3 transgenic mice show increased transepidermal water loss. (A) Neonatal mice were separated from their mothers and weighed over time. Transgenic mice (♦) lose weight faster than nontransgenic littermates (•). Error bars indicate SEM for four mice in each group. Rate of weight loss, mean ± SEM is shown. (B) Weight loss of isolated skin from transepidermal water loss through the epidermis. Graphs show paired comparison of transgenic mouse skin (♦) and nontransgenic littermate skin (▪). Rate of transepidermal water loss, mean ± SEM for eight samples in each group is shown.