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Substrate contact turnover during cell spreading is potentiated by microtubules. A: Video sequence of a spreading fish fibroblast transfected with EGFP-zyxin. (B) As in A but for a cell pretreated with and replated in the presence of 2.5 μg/ml nocodazole. Arrowheads indicate the position of representative contacts throughout the two sequences. Times are given in minutes and seconds. Bar, 10 μm. Video available at http://www.jcb.org/cgi/content/full/146/5/1033/F1/DC1
