Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1999 Sep 6;146(5):1161–1172. doi: 10.1083/jcb.146.5.1161

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 1999 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

ADP-ribosyl cyclase activity of CD38 in isolated osteoclast plasma membranes. The conversion of the NAD⁺ surrogate, NGD⁺, to the nonhydrolyzable fluorescent product, cyclic GDP-ribose (cGDPr) was assessed fluorimetrically (see Materials and Methods for details). Results are expressed as a mean (± SEM) cGDPr formed in nmoles/min/mg isolated plasma membrane protein without treatment (basal) or in the presence of nonimmune mouse serum (IgG5) (NIMS), an antagonist anti-CD38 antibody (Ab; Sigma Chemical Co., 1:500) or NAD⁺ (400 μM). The asterisks represent significant differences compared with basal (P < 0.05).