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. 1981 May;146(2):647–655. doi: 10.1128/jb.146.2.647-655.1981

Serine utilization by Klebsiella aerogenes.

L C Vining, B Magasanik
PMCID: PMC217008  PMID: 6783624

Abstract

Klebsiella aerogenes was found to contain a specific L-serine dehydrase that was induced by threonine, glycine or leucine, but not by its substrate. Cellular concentrations were sensitive to carbon rather than nitrogen sources in the growth medium. A nonspecific isoleucine-sensitive L-threonine dehydrase supplemented the specific L-serine dehydrase activity. K. aerogenes also contains a leucine-inducible L-threonine dehydrogenase which probably initiated a threonine-utilization pathway in which the serine-specific dehydrate participated. Strains that were altered in their ability to metabolize serine differed in either L-serine dehydrase or L-threonine dehydrase activity. Thus, K. aerogenes growing on L-serine as a sole nitrogen source relies upon two enzymes that metabolize the amino acid as subsidiary functions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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