Table 2.

Morbidity and mortality among HIV-infected and HIV-uninfected children <5 years old with severe malarial anaemia

	HIV infected children (N = 78) Years of follow-up = 5.2		HIV uninfected children (N = 769) Years of follow-up = 55.0		† Hazard ratio (HR) or Incidence rate ratio (IRR)	P-value
In the 28 days following first admission with severe malarial anaemia	Episodes or Deaths	Rate per 100 person-years	Episodes or Deaths	Rate per 100 person-Years
Mortality
Death within 7 days of a malaria episode	8	153.8	28	50.9	2.86 (1.30 – 6.29)	0.009
Death within 28 days of a malaria episode	12	230.8	33	60.0	3.70 (1.91 – 7.17)	<0.001
Hospital admissions
Any reason for re-admission	11	211.5	28	50.9	4.05 (1.95 – 8.43)	<0.001
Re-admission due to malaria	5	96.2	13	23.6	3.74 (1.41 – 9.90)	0.008
In the 6 months follow-up (Includes repeat episodes)
Mortality
All cause mortality	26	110.2	50	17.8	5.70 (3.54 – 9.16)	<0.001
Death within 7 days of any malaria episode	12	50.8	33	11.7	3.74 (1.93 – 7.26)	<0.001
Death within 28 days of any malaria episode	19	80.5	41	14.6	4.88 (2.83 – 8.42)	<0.001
Hospital admissions
Any reason for re-admission	18	76.3	66	23.5	2.93 (1.62 – 5.29)	<0.001
Re-admissions due to malaria	7	29.7	26	9.2	2.66 (1.17 – 6.07)	0.02
Malaria incidence
Malaria diagnosed during visits after enrollment	92	394.1	881	313.9	1.12 (0.91 – 1.38)	0.273
Malaria episode >28 days after last malaria episode	54	228.8	582	206.9	0.98 (0.76 – 1.28)	0.895
Unscheduled visits
Unscheduled visits to the clinic	24	101.7	227	80.7	1.14 (0.74 – 1.77)	0.543

† Adjusted for age, sex and baseline quinine treatment status