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. Author manuscript; available in PMC: 2008 Dec 15.
Published in final edited form as: Dev Biol. 2007 Sep 22;312(2):613–622. doi: 10.1016/j.ydbio.2007.09.018

Fig. 3. The gata5 and gata6 genes are functionally redundant for atrial cardiomyocyte differentiation.

Fig. 3

Shown in each panel is a typical representative embryo following processing by whole mount in situ hybridization to detect transcripts for the atrial cardiomyocyte marker amhc at 32 hpf. Samples represent: wild-type embryos (WT), gata4 morphants (G4 MO), gata6 morphants (G6 MO), gata5 morphants (ssG5 MO or tbG5 MO), gata4+5 double morphants (G4+ssG5 MO or G4+tbG5 MO), gata4+6 double morphants (G4+6 MO), and gata5+6 double morphants (ssG5+6 MO and tbG5+6 MO) Despite morphogenetic defects, the atrium is specified in both gata4+6 and gata4+5 double morphants. However, ahmc transcripts are not detectable in gata5+6 double morphants. While these results were reproduced in multiple independent experiments, the number of embryos from the experiment represented in this figure by the phenotype (x) for a given number of embryos (n) is shown in each panel (x/n). Views are either ventral or dorsal, depending on the heart tube position, with anterior to the top.