Table 1.
Comparison of phenotypes in embryos derived from crossing faus26/+ adults, with those embryos derived from wildtype adults, but injected either with the splice site ssG5 MO or translation-blocker (tbG5 MO) morpholinos targeting gata5. The percentage of embryos is shown for each of 4 characteristic phenotypes (fairly normal heart tube, partially fused heart tube, bifid heart, or significant loss of cardiac tissue.
| Heart tube | Partially fused tube | Cardia bifida | Dramatic decrease or absence of cardiac progenitors | |
|---|---|---|---|---|
| ssG5 MO (51 embryos) | 12% | 24% | 61% | 4% |
| tbG5 MO (31 embryos) | 0% | 0% | 100% | 0% |
| Embryos from s26 hets crossed (68 embryos) | 66% (assumed to be wt and +/s26) | 4% | 27% | 3% |