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. 2007 Apr 5;581(Pt 3):1043–1056. doi: 10.1113/jphysiol.2007.129999

Figure 5.

Figure 5

Voltage dependence of AMPAR-mEPSCs All events were recorded in the presence of strychnine (5 μm), picrotoxin (100 μm), APV (50 μm) and TTX (1 μm) to isolate AMPA mEPSCs at all holding potentials. A, I–V relationship of averaged mEPSCs at 33 hpf (n = 4–10 embryos) at different holding potentials ranging from −80 mV to +80 mV in 20 mV increments; right I–V plot of pooled data was linear B, averaged mEPSC I–V relationship at 48 hpf (n = 4–9 larvae); right I–V plot of pooled data at different holding potentials from −80 mV to +80 mV, was outwardly rectified. AMPA mEPSCs at +20 mV in 48 hpf fish are omitted because they were small in amplitude and were difficult to isolate above background noise.