Skip to main content
. 2007 Mar 22;581(Pt 3):961–970. doi: 10.1113/jphysiol.2006.121822

Figure 2.

Figure 2

LTP does not require NMDA receptor activation or a rise in postsynaptic calcium A, averaged normalized EPSC amplitude is plotted for four neurons loaded with the calcium chelator BAPTA (10 mm). The normalized paired-pulse ratio for these cells is plotted in the lower panel. B, average normalized EPSC is plotted for 6 cells. Following a short baseline, d-APV (30 μm) was applied and had no effect on baseline transmission. Tetanic stimulation in the presence of APV leads to LTP. Subsequent washout of APV has no effect on synaptic transmission. The normalized paired-pulse ratio for these cells is plotted in the lower panel.