Table 1.

Thigh fatty acid (FA) kinetics during graded knee extension exercise

	Rest	25% Wmax	65% Wmax	85% Wmaz	ANOVA Rest & Ex.	ANOVA Intensity
Femoral arterial FA concentration (μmol l−1)	615 ± 54 *	687 ± 80	720 ± 111	720 ± 111	†
FA delivery (μmol min−1)	85 ± 11 *	902 ± 86 #	1369 ± 155	1612 ± 169	†	‡
Femoral venous FA concentration (μmol l−1)	651 ± 38	638 ± 44	673 ± 59	679 ± 58
Net thigh FA uptake (μmol min−1)	0 ± 3 *	59 ± 15	71 ± 11	81 ± 18	†
Fractional extraction (%)	38 ± 2 *	21 ± 2 #	16 ± 2	14 ± 2	†	‡
Total thigh FA uptake (μmol min−1)	31 ± 4 *	183 ± 16	206 ± 23	224 ± 25	†
Thigh FA release (μmol min−1)	31 ± 2 *	124 ± 14	136 ± 16	142 ± 19	†
% FA uptake oxidized	17 ± 21 *	66 ± 10	76 ± 16	80 ± 14	†
Thigh plasma FA oxidation (μmol min−1)	5 ± 1 *	114 ± 15	162 ± 30	180 ± 31 $	†	‡
Non-corrected thigh plasma FA oxidation (μmol min−1)	1 ± 5 *	67 ± 5	81 ± 15	91 ± 15	†

Tracer data are averaged across the last 15 min of rest, the last 30 min during the initial 45 min of exercise and the last 20 min during the final 35 min of exercise. Other data are averaged across the measurement period. Values are means ± s.e.m.

^*P < 0.05 Rest versus 25, 65 & 85% W_max;

^†ANOVA effect of exercise intensity including rest.

^‡P < 0.05 ANOVA effect of exercise intensity;

^#P < 0.05 25% W_maxversus 65% W_max and 85% W_max;

^$P < 0.05 25% and 65% W_maxversus 85% W_max.