Skip to main content
. 2007 Mar 29;581(Pt 3):1293–1307. doi: 10.1113/jphysiol.2007.130872

Figure 2.

Figure 2

Effects of selective blockade of muscarinic receptor subtypes in RVLM on NOS I–PKG or NOS II–peroxynitrite signalling cascade in ventrolateral medulla during Mev intoxication Representative Western blots (insets), or percentage of NOS I, II or III, PKG or nitrotyrosine (NT) relative to β-actin protein, detected from the ventrolateral medulla 30 min (Phase I) or 180 min (Phase II) after animals received bilateral microinjection into RVLM of Mev (10 nmol) or aCSF, given together with individual muscarinic receptor antagonists or their solvent (Vehicle). Values are mean ± s.e.m. of triplicate analyses, n = 5–6 animals per experimental group. *P < 0.05 vs. aCSF + aCSF group, and +P < 0.05 vs. Vehicle + Mev group in the Scheffé's multiple-range analysis. ND, below detection limit.