Figure 3.

Effects of loss-of-function manipulations of NF-κB in RVLM on cardiovascular responses during Mev intoxication Temporal changes in MSAP, HR or power density of LF component of SAP spectrum in animals that received microinjection bilaterally into the RVLM (at arrow) of Mev (10 nmol) or aCSF, given together with NF-κB inhibitors DDTC or PDTC (75 nmol) or their solvent, double distilled water (ddH₂O) (left panels); or 24 h after animals received microinjection into the bilateral RVLM of double-stranded κB decoy or scrambled (SC) DNA (100 pmol) (right panels). Values are mean ± s.e.m., n = 5–6 animals per experimental group. *P < 0.05 vs. ddH₂O + aCSF group and ⁺P < 0.05 vs. ddH₂O + Mev group at corresponding time points in the Scheffé's multiple-range analysis.