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The 5α-THDOC directly activates α6β2δ receptors A, 5α-THDOC-induced current traces. The dotted line indicates the zero-current level; the shaded area represents the spontaneous activity. The thick lines above the current traces represent the duration of 5α-THDOC applications. B, the 5α-THDOC concentration–response relationship and fit of data point to a Hill equation.
