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Parameters obtained from fitting the Hill equation to data from Picrotoxinin-, Furosemide- and Zn2+-dependent block of the spontaneous current
| GABAAR subtype | IC50 (μm) | nH | Maximal inhibition | n |
|---|---|---|---|---|
| α6β2δ | ||||
| Picrotoxinin | 0.16 ± 0.02 | 1.26 ± 0.06 | 93.68 ± 2.29% | 6 |
| Furosemide | 12.31 ± 0.51 | 1.03 ± 0.05 | 75.82 ± 4.59% | 9 |
| Zn2+ | 1.42 ± 0.21 | 0.99 ± 0.08 | 56.77 ± 4.18% | 5 |
| α6β1δ | ||||
| Picrotoxinin | 0.28 ± 0.05 | 0.95 ± 0.06 | 86.06 ± 2.68% | 5 |
| α6β3δ | ||||
| Picrotoxinin | 0.28 ± 0.05 | 1.18 ± 0.09 | 93.04 ± 2.04% | 6 |
